IST Dataset
IST.RdThe International Stroke Trial Dataset
Format
A data frame with 19435 rows and 112 columns:
- AGE
Randomisation data: Age in years
- CMPLASP
Other data and derived variables: Compliant for aspirin
- CMPLHEP
Other data and derived variables: Compliant for heparin
- CNTRYNUM
Other data and derived variables: Country code
- COUNTRY
Other data and derived variables: Abbreviated country code
- DALIVE
Recurrent stroke within 14 days: Discharged alive from hospital
- DALIVED
Recurrent stroke within 14 days: Date Discharged alive from hospital
- DAP
Data collected on 14 day/discharge form about treatments given in hospital: Non trial antiplatelet drug (Y/N)
- DASP14
Data collected on 14 day/discharge form about treatments given in hospital: Aspirin given for 14 days or till death or discharge (Y/N)
- DASPLT
Data collected on 14 day/discharge form about treatments given in hospital: Discharged on long term aspirin (Y/N)
- DAYLOCAL
Randomisation data: Estimate of local day of week (assuming RDATE is Oxford)
- DCAA
Data collected on 14 day/discharge form about treatments given in hospital: Calcium antagonists (Y/N)
- DCAREND
Data collected on 14 day/discharge form about treatments given in hospital: Carotid surgery (Y/N)
- DDEAD
Other events within 14 days: Dead on discharge form
- DDEADC
Other events within 14 days: Cause of death (1-Initial stroke/2-Recurrent stroke (ischaemic or unknown /3-Recurrent stroke (haemorrhagic)/4-Pneumonia /5-Coronary heart disease/6-Pulmonary embolism /7-Other vascular or unknown/8-Non-vascular/0-unknown)
- DDEADD
Date of dead on discharge form (yyyy/mm/dd); NOTE: this death is not necessarily within 14 days of randomisation
- DDEADX
Other events within 14 days: Comment on death
- DDIAGHA
Final diagnosis of initial event: Haemorrhagic stroke
- DDIAGISC
Final diagnosis of initial event: Ischaemic stroke
- DDIAGUN
Final diagnosis of initial event: Indeterminate stroke
- DEAD1
Indicator variables for specific causes of death: Initial stroke
- DEAD2
Indicator variables for specific causes of death: Reccurent ischaemic/unknown stroke
- DEAD3
Indicator variables for specific causes of death: Reccurent haemorrhagic stroke
- DEAD4
Indicator variables for specific causes of death: Pneumonia
- DEAD5
Indicator variables for specific causes of death: Coronary heart disease
- DEAD6
Indicator variables for specific causes of death: Pulmonary embolism
- DEAD7
Indicator variables for specific causes of death: Other vascular or unknown
- DEAD8
Indicator variables for specific causes of death: Non vascular
- DGORM
Data collected on 14 day/discharge form about treatments given in hospital: Glycerol or manitol (Y/N)
- DHAEMD
Data collected on 14 day/discharge form about treatments given in hospital: Haemodilution (Y/N)
- DHH14
Data collected on 14 day/discharge form about treatments given in hospital: Medium dose heparin given for 14 days etc in pilot (combine with above)
- DIED
Other data and derived variables: Indicator variable for death (1=died; 0=did not die)
- DIVH
Data collected on 14 day/discharge form about treatments given in hospital: Non trial intravenous heparin (Y/N)
- DLH14
Data collected on 14 day/discharge form about treatments given in hospital: Low dose heparin given for 14 days or till death/discharge (Y/N)
- DMAJNCH
Data collected on 14 day/discharge form about treatments given in hospital: Major non-cerebral haemorrhage (Y/N)
- DMAJNCHD
Data collected on 14 day/discharge form about treatments given in hospital: Date of Major non-cerebral haemorrhage (yyyy/mm/dd)
- DMAJNCHX
Data collected on 14 day/discharge form about treatments given in hospital: Comment of Major non-cerebral haemorrhage
- DMH14
Data collected on 14 day/discharge form about treatments given in hospital: Date of Major non-cerebral haemorrhage (yyyy/mm/dd)
- DNOSTRK
Final diagnosis of initial event: Not a stroke
- DNOSTRKX
Final diagnosis of initial event: Comment on Not a stroke
- DOAC
Data collected on 14 day/discharge form about treatments given in hospital: Other anticoagulants (Y/N)
- DPE
Other events within 14 days: Pulmonary embolism
- DPED
Other events within 14 days: Date of Pulmonary embolism (yyyy/mm/dd)
- DPLACE
Other events within 14 days: Discharge destination (A-Home /B-Relatives home /C-Residential care /D-Nursing home /E-Other hospital departments /U-Unknown)
- DRSH
Recurrent stroke within 14 days: Haemorrhagic stroke
- DRSHD
Recurrent stroke within 14 days: Date of Haemorrhagic stroke (yyyy/mm/dd)
- DRSISC
Recurrent stroke within 14 days: Ischaemic recurrent stroke
- DRSISCD
Recurrent stroke within 14 days: Date of Ischaemic recurrent stroke (yyyy/mm/dd)
- DRSUNK
Recurrent stroke within 14 days: Unknown type
- DRSUNKD
Recurrent stroke within 14 days: Date of Unknown type (yyyy/mm/dd)
- DSCH
Data collected on 14 day/discharge form about treatments given in hospital: Non trial subcutaneous heparin (Y/N)
- DSIDE
Data collected on 14 day/discharge form about treatments given in hospital: Other side effect (Y/N)
- DSIDED
Data collected on 14 day/discharge form about treatments given in hospital: Date of Other side effect
- DSIDEX
Data collected on 14 day/discharge form about treatments given in hospital: Comment of Other side effect
- DSTER
Data collected on 14 day/discharge form about treatments given in hospital: Steroids (Y/N)
- DTHROMB
Data collected on 14 day/discharge form about treatments given in hospital: Thrombolysis (Y/N)
- DVT14
Indicator variables for specific causes of death: Indicator of deep vein thrombosis on discharge form
- EXPD14
Other data and derived variables: Predicted probability of death at 14 days
- EXPD6
Other data and derived variables: Predicted probability of death at 6 month
- EXPDD
Other data and derived variables: Predicted probability of death/dependence at 6 month
- FAP
Data collected at 6 months: On antiplatelet drugs
- FDEAD
Data collected at 6 months: Dead at six month follow-up (Y/N)
- FDEADC
Data collected at 6 months: Cause of death (1-Initial stroke /2-Recurrent stroke (ischaemic or unknown) /3-Recurrent stroke (haemorrhagic) /4-Pneumonia /5-Coronary heart disease /6-Pulmonary embolism /7-Other vascular or unknown /8-Non-vascular /0-unknown)
- FDEADD
Data collected at 6 months: Date of death; NOTE: this death is not necessarily within 6 months of randomisation
- FDEADX
Data collected at 6 months: Comment on death
- FDENNIS
Data collected at 6 months: Dependent at 6 month follow-up (Y/N)
- FLASTD
Data collected at 6 months: Date of last contact
- FOAC
Data collected at 6 months: On anticoagulants
- FPLACE
Data collected at 6 months: Place of residance at 6 month follow-up ( A-Home /B-Relatives home /C-Residential care /D-Nursing home /E-Other hospital departments /U-Unknown)
- FRECOVER
Data collected at 6 months: Fully recovered at 6 month follow-up (Y/N)
- FU1_COMP
Other data and derived variables: Date discharge form completed
- FU1_RECD
Other data and derived variables: Date discharge form received
- FU2_DONE
Other data and derived variables: Date 6 month follow-up done
- H14
Indicator variables for specific causes of death: Cerebral bleed/heamorrhagic stroke within 14 days; this is slightly wider definition than DRSH an is used for analysis of cerebral bleeds
- HOSPNUM
Randomisation data: Hospital number
- HOURLOCAL
Randomisation data: Local time – hours
- HTI14
Indicator variables for specific causes of death: Indicator of haemorrhagic transformation within 14 days
- ID14
Other data and derived variables: Indicator of death at 14 days
- ISC14
Indicator variables for specific causes of death: Indicator of ischaemic stroke within 14 days
- MINLOCAL
Randomisation data: Local time – minutes
- NCB14
Indicator variables for specific causes of death: Indicator of any non-cerebral bleed within 14 days
- NCCODE
Other data and derived variables: Coding of compliance (see Table 3) doi:10.1186/1745-6215-13-24
- NK14
Indicator variables for specific causes of death: Indicator of indeterminate stroke within 14 days
- OCCODE
Other data and derived variables: Six month outcome ( 1-dead /2-dependent /3-not recovered /4-recovered /8 or 9 – missing status
- ONDRUG
Data collected on 14 day/discharge form about treatments given in hospital: Estimate of time in days on trial treatment
- PE14
Indicator variables for specific causes of death: Indicator of pulmonary embolism within 14 days
- RASP3
Randomisation data: Aspirin within 3 days prior to randomisation (Y/N)
- RATRIAL
Randomisation data: Atrial fibrillation (Y/N); not coded for pilot phase - 984 patients
- RCONSC
Randomisation data: Conscious state at randomisation (F - fully alert, D - drowsy, U - unconscious)
- RCT
Randomisation data: CT before randomisation (Y/N)
- RDATE
Randomisation data: Date of randomisation
- RDEF1
Randomisation data: Face deficit (Y/N/C=can't assess)
- RDEF2
Randomisation data: Arm/hand deficit (Y/N/C=can't assess)
- RDEF3
Randomisation data: Leg/foot deficit (Y/N/C=can't assess)
- RDEF4
Randomisation data: Dysphasia (Y/N/C=can't assess)
- RDEF5
Randomisation data: Hemianopia (Y/N/C=can't assess)
- RDEF6
Randomisation data: Visuospatial disorder (Y/N/C=can't assess)
- RDEF7
Randomisation data: Brainstem/cerebellar signs (Y/N/C=can't assess)
- RDEF8
Randomisation data: Other deficit (Y/N/C=can't assess)
- RDELAY
Randomisation data: Delay between stroke and randomisation in hours
- RHEP24
Randomisation data: Heparin within 24 hours prior to randomisation (Y/N)
- RSBP
Randomisation data: Systolic blood pressure at randomisation (mmHg)
- RSLEEP
Randomisation data: Symptoms noted on waking (Y/N)
- RVISINF
Randomisation data: Infarct visible on CT (Y/N)
- RXASP
Randomisation data: Trial aspirin allocated (Y/N)
- RXHEP
Randomisation data: Trial heparin allocated (M/L/N) \[M is coded as H=high in pilot\]
- SET14D
Other data and derived variables: Know to be dead or alive at 14 days (1=Yes, 0=No); this does not necessarily mean that we know outcome at 6 monts – see OCCODE for this
- SEX
Randomisation data: M=male; F=female
- STRK14
Indicator variables for specific causes of death: Indicator of any stroke within 14 days
- STYPE
Randomisation data: Stroke subtype (TACS/PACS/POCS/LACS/other)
- TD
Other data and derived variables: Time of death or censoring in days
- TRAN14
Indicator variables for specific causes of death: Indicator of major non-cerebral bleed within 14 days
...
Details
Obtained from Sandercock, Peter; Niewada, Maciej; Czlonkowska, Anna. (2011). International Stroke Trial database (version 2), [dataset]. University of Edinburgh. Department of Clinical Neurosciences. doi:10.7488/ds/104 Under ODC-by licence
Author
Sandercock P et al. Peter.Sandercock@ed.ac.uk